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Our research is all about our patients.

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What Are Clinical Trials and Studies?

Clinical research is an essential tool to assess the safety and efficacy of a new medical treatment or drug therapy. Clinical trials may compare a new treatment to an existing one, to a placebo that has no active ingredients, or to no intervention. This is how researchers and medical professionals find out if a new drug, diet, device, or other medical treatment is both safe and effective.

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FREoE Study

The FREoE study is a novel diet study for children ages 2 to 18 who suffer from symptoms of EoE. Although there is increasing evidence that consumption of food additives may impact health, scientists have not tested how food additives influence clinical outcomes in EoE. While elimination of dairy from the diet provides relief for some EoE patients, we are interested in whether elimination of both common food additives and dairy from the diet results in even better outcomes for EoE patients.

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PPIREoE Study

Proton pump inhibitors (PPIs) are one of the three approved therapies for treatment of eosinophilic esophagitis. While safe and effective, a large percentage of EoE patients fail to respond to PPIs due to a complex mix of environmental and genetic factors that are unique to the individual. Dr. Franciosi is leading a group of internationally recognized EoE researchers to identify factors that limit response to PPIs in EoE and will use this information to improve individual response.

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PPI Precision Medicine Study

For every drug therapy that is currently on the market, a percentage of the patients who receive the therapy will respond poorly due to variability in individual environmental and genetic factors. Precision Medicine is the study of the factors that associate with poor therapeutic response and the use of this information to improve therapeutic outcomes. This study seeks to establish Precision Medicine recommendations for drug therapies that are routinely used to treat gastrointestinal conditions.

Testimonials

Our Patients Love Our Treatment


“We are beyond grateful to Dr. Franciosi for getting the Transnasal Endoscopy (TNE) started here. My son has had 17 regular endoscopies and it is always such a long and hard process. The TNE procedure was so fast and simple! No more long hospital visits or waiting for anesthesia to wear off. I can't recommend the TNE enough!”
Parent

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Resources

Questions? We are here to help!

Click the link below for additional resources or email us at eoeorlando@nemours.org