I have been a research scientist with Nemours for over twenty years. In that time, I have worked on many research projects that have studied how an individual's genetics determines their response to different drug therapies. I have been a member of the Center for Pharmacogenomics and Translational Research (CPTR) at Nemours Children's Clinic in Jacksonville, Florida, for eleven years. I have an additional seventeen years of molecular research experience.
My collaborations with Drs. Lima, Lang, and Blake of CPTR and Dr. Franciosi, Chief, Division of Gastroenterology, Hepatology, and Nutrition at Nemours Children's Hospital in Orlando, Florida, have been productive, resulting in five primary author publications and an additional eighteen supporting author publications.
Recently, I have been working with Dr. Franciosi to determine the optimum proton pump inhibitor dose for each individual's unique combination of genetic variants. Our goal is to improve individual response to proton pump inhibitor therapy for the treatment of eosinophilic esophagitis, gastroesophageal reflux disease, and other acid-related conditions. I firmly believe that this "personalized medicine" approach is critical to maximizing individual response to our existing therapeutics while minimizing unintended side effects.
You/your child's participation in our clinical studies will help us acquire the data necessary to understand how best to prescribe proton pump inhibitors to children and adolescents.
- 1982 B.S. University of Maryland, College Park, MD
- 1988 Ph.D University of Delaware, Newark, DE
- 1988-1996 Post-Doc Johns Hopkins Univ. School of Medicine, Baltimore, MD
- 1997-1998 Research Associate II, Cellular and Molecular Medicine Laboratory, The Nemours Children’s Clinic, Jacksonville, FL
- 1999- to present Research Scientist, Center for Pharmacogenomics and Translational Research, Nemours Children’s Specialty Care, Jacksonville, FL